Endocrine Abstracts

Introduction: A high prevalence of polycystic ovary syndrome (PCOS) and hyperandrogenism has been described in adult women with type 1 diabetes mellitus (T1DM). Anti-Müllerian hormone (AMH) is secreted by granulosa cells of antral ovarian follicles and its plasma concentration is correlated with the number of small antral follicles. AMH levels are increased in women with PCOS and higher plasma concentration has been observed in prepubertal girls with T1DM. The aim of this...

Aim of the study: Polycystic ovary syndrome (PCOS) is common disease affecting women in reproductive age which leads to anovulation. In pathogenesis of PCOS insulin resistance plays an important role. The aim of the present study was to look for possible relationship between interleukin 18 (IL-18) and insulin resistance in patients with PCOS.Material and Methods: The study was done in 76 patients with PCOS and 40 women without menstrual disturbances. The...